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Genetic ablation of tau improves mitochondrial function and cognitive abilities in the hippocampus

Tau is a key protein for microtubule stability; however, post-translationally modified tau contributes to neurodegenerative diseases by forming tau aggregates in the neurons. Previous reports from our group and others have shown that pathological forms of tau are toxic and impair mitochondrial funct...

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Dades bibliogràfiques
Publicat a:Redox Biol
Autors principals: Jara, Claudia, Aránguiz, Alejandra, Cerpa, Waldo, Tapia-Rojas, Cheril, Quintanilla, Rodrigo A.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072970/
https://ncbi.nlm.nih.gov/pubmed/30077079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.07.010
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