Genetic ablation of tau improves mitochondrial function and cognitive abilities in the hippocampus

Tau is a key protein for microtubule stability; however, post-translationally modified tau contributes to neurodegenerative diseases by forming tau aggregates in the neurons. Previous reports from our group and others have shown that pathological forms of tau are toxic and impair mitochondrial funct...

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Foilsithe in:Redox Biol
Main Authors: Jara, Claudia, Aránguiz, Alejandra, Cerpa, Waldo, Tapia-Rojas, Cheril, Quintanilla, Rodrigo A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2018
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072970/
https://ncbi.nlm.nih.gov/pubmed/30077079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.07.010
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