Utility of targeted deep sequencing for detecting circulating tumor DNA in pancreatic cancer patients

Targeted deep sequencing across broad genomic regions has been used to detect circulating tumor DNA (ctDNA) in pancreatic ductal adenocarcinoma (PDAC) patients. However, since most PDACs harbor a mutation in KRAS, sequencing of broad regions needs to be systemically compared to analyzing only KRAS m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Park, Gahee, Park, Joo Kyung, Son, Dae-Soon, Shin, Seung-Ho, Kim, Yeon Jeong, Jeon, Hyo-Jeong, Lee, Jae, Park, Woong-Yang, Lee, Kwang Hyuck, Park, Donghyun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072791/
https://ncbi.nlm.nih.gov/pubmed/30072705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30100-w
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