Characterization of background noise in capture-based targeted sequencing data

BACKGROUND: Targeted deep sequencing is increasingly used to detect low-allelic fraction variants; it is therefore essential that errors that constitute baseline noise and impose a practical limit on detection are characterized. In the present study, we systematically evaluate the extent to which er...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Park, Gahee, Park, Joo Kyung, Shin, Seung-Ho, Jeon, Hyo-Jeong, Kim, Nayoung K. D., Kim, Yeon Jeong, Shin, Hyun-Tae, Lee, Eunjin, Lee, Kwang Hyuck, Son, Dae-Soon, Park, Woong-Yang, Park, Donghyun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5521083/
https://ncbi.nlm.nih.gov/pubmed/28732520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1275-2
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