Utility of targeted deep sequencing for detecting circulating tumor DNA in pancreatic cancer patients

Targeted deep sequencing across broad genomic regions has been used to detect circulating tumor DNA (ctDNA) in pancreatic ductal adenocarcinoma (PDAC) patients. However, since most PDACs harbor a mutation in KRAS, sequencing of broad regions needs to be systemically compared to analyzing only KRAS m...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Park, Gahee, Park, Joo Kyung, Son, Dae-Soon, Shin, Seung-Ho, Kim, Yeon Jeong, Jeon, Hyo-Jeong, Lee, Jae, Park, Woong-Yang, Lee, Kwang Hyuck, Park, Donghyun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072791/
https://ncbi.nlm.nih.gov/pubmed/30072705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30100-w
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