Loss of glutamate signaling from the thalamus to dorsal striatum impairs motor function and slows the execution of learned behaviors

Parkinson’s disease (PD) is primarily associated with the degeneration of midbrain dopamine neurons, but it is now appreciated that pathological processes like Lewy-body inclusions and cell loss affect several other brain regions, including the central lateral (CL) and centromedian/parafascicular (C...

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Detalhes bibliográficos
Publicado no:NPJ Parkinsons Dis
Main Authors: Melief, Erica J., McKinley, Jonathan W., Lam, Jonathan Y., Whiteley, Nicole M., Gibson, Alec W., Neumaier, John F., Henschen, Charles W., Palmiter, Richard D., Bamford, Nigel S., Darvas, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072777/
https://ncbi.nlm.nih.gov/pubmed/30083593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41531-018-0060-6
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