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Contributions of signaling by dopamine neurons in dorsal striatum to cognitive behaviors corresponding to those observed in Parkinson’s disease

Although the cardinal features of Parkinson’s disease (PD) are motor symptoms, PD also causes cognitive deficits including cognitive flexibility and working memory, which are strongly associated with prefrontal cortex (PFC) functions. Yet, early stage PD is not characterized by pathology in the PFC...

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Hlavní autoři: Darvas, Martin, Henschen, Charles W., Palmiter, Richard D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4001780/
https://ncbi.nlm.nih.gov/pubmed/24491966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.01.017
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