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The Mutation-Associated Neoantigen Functional Expansion of Specific T cells (MANAFEST) assay: a sensitive platform for monitoring antitumor immunity

Mutation-associated neoantigens (MANAs) are a target of antitumor T-cell immunity. Sensitive, simple, and standardized assays are needed to assess the repertoire of functional MANA-specific T cells in oncology. Assays analyzing in vitro cytokine production such as ELISpot and intracellular cytokine...

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Vydáno v:Cancer Immunol Res
Hlavní autoři: Danilova, Ludmila, Anagnostou, Valsamo, Caushi, Justina X., Sidhom, John-William, Guo, Haidan, Chan, Hok Yee, Suri, Prerna, Tam, Ada, Zhang, Jiajia, El Asmar, Margueritta, Marrone, Kristen A., Naidoo, Jarushka, Brahmer, Julie R., Forde, Patrick M., Baras, Alexander S., Cope, Leslie, Velculescu, Victor E., Pardoll, Drew M., Housseau, Franck, Smith, Kellie N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072595/
https://ncbi.nlm.nih.gov/pubmed/29895573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0129
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