The Mutation-Associated Neoantigen Functional Expansion of Specific T cells (MANAFEST) assay: a sensitive platform for monitoring antitumor immunity

Mutation-associated neoantigens (MANAs) are a target of antitumor T-cell immunity. Sensitive, simple, and standardized assays are needed to assess the repertoire of functional MANA-specific T cells in oncology. Assays analyzing in vitro cytokine production such as ELISpot and intracellular cytokine...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Danilova, Ludmila, Anagnostou, Valsamo, Caushi, Justina X., Sidhom, John-William, Guo, Haidan, Chan, Hok Yee, Suri, Prerna, Tam, Ada, Zhang, Jiajia, El Asmar, Margueritta, Marrone, Kristen A., Naidoo, Jarushka, Brahmer, Julie R., Forde, Patrick M., Baras, Alexander S., Cope, Leslie, Velculescu, Victor E., Pardoll, Drew M., Housseau, Franck, Smith, Kellie N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072595/
https://ncbi.nlm.nih.gov/pubmed/29895573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0129
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