Loss of XIST in breast cancer activates MSN-c-Met and reprograms microglia via exosomal microRNA to promote brain metastasis

Up to 30% of patients with metastatic breast cancer eventually develop brain metastasis, yet the pathological mechanism behind this development remains poorly understood. Here we profiled long non-coding RNAs in brain metastatic tumors from breast cancer patients and found that the X-inactive specif...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Xing, Fei, Liu, Yin, Wu, Shin-Ying, Wu, Kerui, Sharma, Sambad, Mo, Yin-Yuan, Feng, Jiamei, Sanders, Stephanie, Jin, Guangxu, Singh, Ravi, Vidi, Pierre-Alexandre, Tyagi, Abhishek, Chan, Michael D., Ruiz, Jimmy, Debinski, Waldemar, Pasche, Boris C., Lo, Hui-Wen, Metheny-Barlow, Linda J., D’Agostino, Ralph B., Watabe, Kounosuke
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072593/
https://ncbi.nlm.nih.gov/pubmed/30026327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-1102
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