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Studies on enantioselectivity of chiral 4-acetylamino-6-alkyloxy-2-alkylthiopyrimidines acting as antagonists of the human A(3) adenosine receptor

Three A(3) adenosine receptor (AR) antagonists (1–3) selected from 4-acylamino-6-alkyloxy-2-alkylthiopyrimidines previously investigated by us were modified by inserting a methyl group on their ether or thioether side chains. These compounds gave us the chance to evaluate whether their higher lipoph...

詳細記述

保存先:
書誌詳細
出版年:Medchemcomm
主要な著者: Cosimelli, Barbara, Greco, Giovanni, Laneri, Sonia, Novellino, Ettore, Sacchi, Antonia, Collina, Simona, Rossi, Daniela, Cosconati, Sandro, Barresi, Elisabetta, Taliani, Sabrina, Trincavelli, Maria Letizia, Martini, Claudia
フォーマット: Artigo
言語:Inglês
出版事項: Royal Society of Chemistry 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072526/
https://ncbi.nlm.nih.gov/pubmed/30108902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00375g
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