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Synthesis and biological evaluation of memantine nitrates as a potential treatment for neurodegenerative diseases
A series of memantine nitrate derivatives, as dual functional compounds with neuroprotective and vasodilatory activity for neurodegenerative diseases, was designed and synthesized. These compounds combined the memantine skeleton and a nitrate moiety, and thus inhibited the N-methyl-d-aspartic acid r...
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| Publicado no: | Medchemcomm |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072337/ https://ncbi.nlm.nih.gov/pubmed/30108699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00509h |
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