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Matched-pair, (86)Y/(90)Y-labeled, Bivalent RGD/Bombesin Antagonist, [RGD-Glu-[DO3A]-6-Ahx-RM2], as a Potential Theranostic Agent for Prostate Cancer

INTRODUCTION: In this study, we describe development of a true matched-pair theranostic agent that is able to target the α(V)β(3) integrin and the gastrin releasing peptide receptor (GRPR). We herein describe methods to metallate and characterize the new conjugate and to validate its biological effi...

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Dettagli Bibliografici
Pubblicato in:Nucl Med Biol
Autori principali: Bandara, Nilantha, Stott Reynolds, Tamila J., Schehr, Rebecca, Bandari, Rajendra P., Diebolder, Philipp J., Krieger, Stephanie, Xu, Jingli, Miao, Yubin, Rogers, Buck E., Smith, Charles J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072280/
https://ncbi.nlm.nih.gov/pubmed/29929115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2018.06.001
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