Matched-pair, (86)Y/(90)Y-labeled, Bivalent RGD/Bombesin Antagonist, [RGD-Glu-[DO3A]-6-Ahx-RM2], as a Potential Theranostic Agent for Prostate Cancer

INTRODUCTION: In this study, we describe development of a true matched-pair theranostic agent that is able to target the α(V)β(3) integrin and the gastrin releasing peptide receptor (GRPR). We herein describe methods to metallate and characterize the new conjugate and to validate its biological effi...

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Détails bibliographiques
Publié dans:Nucl Med Biol
Auteurs principaux: Bandara, Nilantha, Stott Reynolds, Tamila J., Schehr, Rebecca, Bandari, Rajendra P., Diebolder, Philipp J., Krieger, Stephanie, Xu, Jingli, Miao, Yubin, Rogers, Buck E., Smith, Charles J.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072280/
https://ncbi.nlm.nih.gov/pubmed/29929115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2018.06.001
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