Synthesis and Biological Evaluation of Copper-64 Radiolabeled [DUPA-6-Ahx-(NODAGA)-5-Ava-BBN(7-14)NH(2)], a Novel Bivalent Targeting Vector Having Affinity for Two Distinct Biomarkers (GRPr/PSMA) of Prostate Cancer

Gastrin-releasing peptide receptors (GRPr) and prostate-specific membrane antigen (PSMA) are two identifying biomarkers expressed in very high numbers on prostate cancer cells and could serve as a useful tool for molecular targeting and diagnosis of disease via positron-emission tomography (PET). Th...

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Main Authors: Bandari, Rajendra Prasad, Jiang, Zongrun, Reynolds, Tamila Stott, Bernskoetter, Nicole E., Szczodroski, Ashley F., Bassuner, Kurt J., Kirkpatrick, Daniel L., Rold, Tammy L., Sieckman, Gary L., Hoffman, Timothy J., Connors, James P., Smith, Charles J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041584/
https://ncbi.nlm.nih.gov/pubmed/24508213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2014.01.001
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