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Matched-pair, (86)Y/(90)Y-labeled, Bivalent RGD/Bombesin Antagonist, [RGD-Glu-[DO3A]-6-Ahx-RM2], as a Potential Theranostic Agent for Prostate Cancer

INTRODUCTION: In this study, we describe development of a true matched-pair theranostic agent that is able to target the α(V)β(3) integrin and the gastrin releasing peptide receptor (GRPR). We herein describe methods to metallate and characterize the new conjugate and to validate its biological effi...

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Detalhes bibliográficos
Publicado no:Nucl Med Biol
Main Authors: Bandara, Nilantha, Stott Reynolds, Tamila J., Schehr, Rebecca, Bandari, Rajendra P., Diebolder, Philipp J., Krieger, Stephanie, Xu, Jingli, Miao, Yubin, Rogers, Buck E., Smith, Charles J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072280/
https://ncbi.nlm.nih.gov/pubmed/29929115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2018.06.001
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