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A marginalized two-part Beta regression model for microbiome compositional data

In microbiome studies, an important goal is to detect differential abundance of microbes across clinical conditions and treatment options. However, the microbiome compositional data (quantified by relative abundance) are highly skewed, bounded in [0, 1), and often have many zeros. A two-part model i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Comput Biol
Egile Nagusiak: Chai, Haitao, Jiang, Hongmei, Lin, Lu, Liu, Lei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072097/
https://ncbi.nlm.nih.gov/pubmed/30036363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006329
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