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A marginalized two-part Beta regression model for microbiome compositional data

In microbiome studies, an important goal is to detect differential abundance of microbes across clinical conditions and treatment options. However, the microbiome compositional data (quantified by relative abundance) are highly skewed, bounded in [0, 1), and often have many zeros. A two-part model i...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Chai, Haitao, Jiang, Hongmei, Lin, Lu, Liu, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072097/
https://ncbi.nlm.nih.gov/pubmed/30036363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006329
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