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The TCR is randomly distributed on the plasma membrane of resting antigen-experienced T cells

It is the main function of T cells to identify harmful antigens as quickly and precisely as possible. Super-resolution microscopy data has indicated that global clustering of the T cell receptor (TCR) occurs prior to T cell activation. Such pre-activation clustering has been interpreted as represent...

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Dettagli Bibliografici
Pubblicato in:Nat Immunol
Autori principali: Rossboth, Benedikt, Arnold, Andreas M., Ta, Haisen, Platzer, René, Kellner, Florian, Huppa, Johannes B., Brameshuber, Mario, Baumgart, Florian, Schütz, Gerhard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071872/
https://ncbi.nlm.nih.gov/pubmed/30013143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-018-0162-7
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