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Synthesis and antiplasmodial activity of purine-based C-nucleoside analogues

A series of homologous C-nucleoside mimics have been synthesized via an efficient and facile synthetic protocol involving the conjugate addition of purine to sugar derived olefinic ester in good yields. The synthesized compounds were evaluated for their antiplasmodial activity in vitro against both...

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Vydáno v:Medchemcomm
Hlavní autoři: Singh, Kartikey, Joshi, Prince, Mahar, Rohit, Baranwal, Pragati, Shukla, Sanjeev K., Tripathi, Renu, Tripathi, Rama Pati
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071838/
https://ncbi.nlm.nih.gov/pubmed/30109012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00098k
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