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Synthesis and antiplasmodial activity of purine-based C-nucleoside analogues

A series of homologous C-nucleoside mimics have been synthesized via an efficient and facile synthetic protocol involving the conjugate addition of purine to sugar derived olefinic ester in good yields. The synthesized compounds were evaluated for their antiplasmodial activity in vitro against both...

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Publicado en:Medchemcomm
Main Authors: Singh, Kartikey, Joshi, Prince, Mahar, Rohit, Baranwal, Pragati, Shukla, Sanjeev K., Tripathi, Renu, Tripathi, Rama Pati
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071838/
https://ncbi.nlm.nih.gov/pubmed/30109012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00098k
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