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Efficient Biocatalytic Synthesis of Dihalogenated Purine Nucleoside Analogues Applying Thermodynamic Calculations

The enzymatic synthesis of nucleoside analogues has been shown to be a sustainable and efficient alternative to chemical synthesis routes. In this study, dihalogenated nucleoside analogues were produced by thermostable nucleoside phosphorylases in transglycosylation reactions using uridine or thymid...

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Publicado en:Molecules
Main Authors: Yehia, Heba, Westarp, Sarah, Röhrs, Viola, Kaspar, Felix, Giessmann, Robert T., Klare, Hendrik F.T., Paulick, Katharina, Neubauer, Peter, Kurreck, Jens, Wagner, Anke
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070685/
https://ncbi.nlm.nih.gov/pubmed/32093094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25040934
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