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The Peculiar Case of the Hyper‐thermostable Pyrimidine Nucleoside Phosphorylase from Thermus thermophilus

The poor solubility of many nucleosides and nucleobases in aqueous solution demands harsh reaction conditions (base, heat, cosolvent) in nucleoside phosphorylase‐catalyzed processes to facilitate substrate loading beyond the low millimolar range. This, in turn, requires enzymes that can withstand th...

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Publicat a:Chembiochem
Autors principals: Kaspar, Felix, Neubauer, Peter, Kurreck, Anke
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8247850/
https://ncbi.nlm.nih.gov/pubmed/33258231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000679
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