Benzylsulfanyl benzo-heterocycle amides and hydrazones as new agents against drug-susceptible and resistant Mycobacterium tuberculosis

A series of benzylsulfanyl benzo-heterocycle amides and hydrazones were synthesized and evaluated for anti-tubercular activities. The isonicotinyl hydrazone derivatives 12d, 12e and 12f exhibited good anti-tubercular activity against Mycobacterium tuberculosis H(37)Rv (ATCC #27294) with MIC values o...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Lu, Xiaoyun, Hu, Xianglong, Liu, Zhiyong, Zhang, Tianyu, Wang, Ruibing, Wan, Baojie, Franzblau, Scott G., You, Qidong
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071830/
https://ncbi.nlm.nih.gov/pubmed/30108841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00146k
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