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Discovery of potential antifungal triazoles: design, synthesis, biological evaluation, and preliminary antifungal mechanism exploration

A series of triazoles as miconazole analogues was designed, synthesized and characterized by IR, NMR, MS and HRMS. All the newly prepared compounds were screened for their antifungal activities against five kinds of fungi. The bioactive assay showed that most of the synthesized compounds exhibited g...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Zhang, Yuan, Damu, Guri L. V., Cui, Sheng-Feng, Mi, Jia-Li, Tangadanchu, Vijai Kumar Reddy, Zhou, Cheng-He
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071786/
https://ncbi.nlm.nih.gov/pubmed/30108874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00112f
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