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Insights into conformational changes in AlkD bound to DNA with a yatakemycin adduct from computational simulations
Structural integrity of DNA molecules is necessary for their information storage function. Cells rely on a number of pathways to ensure that the damage to DNA induced by endogenous and exogenous reagents is repaired. AlkD, a base excision enzyme, removes a damaged nucleobase by cleaving a glycosidic...
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| Publicado no: | Theor Chem Acc |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6071674/ https://ncbi.nlm.nih.gov/pubmed/30078993 |
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