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Upregulation of dNTP Levels After Telomerase Inactivation Influences Telomerase-Independent Telomere Maintenance Pathway Choice in Saccharomyces cerevisiae

In 10–15% of cancers, telomere length is maintained by a telomerase-independent, recombination-mediated pathway called alternative lengthening of telomeres (ALT). ALT mechanisms were first seen, and have been best studied, in telomerase-null Saccharomyces cerevisiae cells called “survivors”. There a...

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Detalles Bibliográficos
Publicado en:G3 (Bethesda)
Main Authors: van Mourik, Paula M., de Jong, Jannie, Sharma, Sushma, Kavšek, Alan, Chabes, Andrei, Chang, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071591/
https://ncbi.nlm.nih.gov/pubmed/29848621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200280
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