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HIV-1 autoreactive antibodies: are they good or bad for HIV-1 prevention?

A new crystal structure of an anti–HIV-1 envelope antibody bound to an envelope–receptor complex shows the antibody binding both the HIV-1 envelope and the CD4 receptor, raising the question of what the role of antibody autoreactivity in host responses to HIV-1 may be.

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Struct Mol Biol
Prif Awduron: Haynes, Barton F, Nicely, Nathan I, Alam, S Munir
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071409/
https://ncbi.nlm.nih.gov/pubmed/20442740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb0510-543
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