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HIV-1 autoreactive antibodies: are they good or bad for HIV-1 prevention?

A new crystal structure of an anti–HIV-1 envelope antibody bound to an envelope–receptor complex shows the antibody binding both the HIV-1 envelope and the CD4 receptor, raising the question of what the role of antibody autoreactivity in host responses to HIV-1 may be.

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Haynes, Barton F, Nicely, Nathan I, Alam, S Munir
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071409/
https://ncbi.nlm.nih.gov/pubmed/20442740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb0510-543
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