HSV as A Platform for the Generation of Retargeted, Armed, and Reporter-Expressing Oncolytic Viruses

Previously, we engineered oncolytic herpes simplex viruses (o-HSVs) retargeted to the HER2 (epidermal growth factor receptor 2) tumor cell specific receptor by the insertion of a single chain antibody (scFv) to HER2 in gD, gH, or gB. Here, the insertion of scFvs to three additional cancer targets—EG...

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Vydáno v:Viruses
Hlavní autoři: Menotti, Laura, Avitabile, Elisa, Gatta, Valentina, Malatesta, Paolo, Petrovic, Biljana, Campadelli-Fiume, Gabriella
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070899/
https://ncbi.nlm.nih.gov/pubmed/29966356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v10070352
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