Effects of Sepantronium Bromide (YM-155) on the Whole Transcriptome of MDA-MB-231 Cells: Highlight on Impaired ATR/ATM Fanconi Anemia DNA Damage Response

Sepantronium bromide (YM-155) is believed to elicit apoptosis and mitotic arrest in tumor cells by reducing (BIRC5, survivin) mRNA. In this study, we monitored changes in survivin mRNA and protein after treating MDA-MB-231 cells with YM-155 concurrent with evaluation of whole transcriptomic (WT) mRN...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Genomics Proteomics
Egile Nagusiak: MAZZIO, ELIZABETH A, LEWIS, CHARLES A, ELHAG, RASHID, SOLIMAN, KARAM F
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Institute of Anticancer Research 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070710/
https://ncbi.nlm.nih.gov/pubmed/29976630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20083
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