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Matrine Exerts Antidepressant-Like Effects on Mice: Role of the Hippocampal PI3K/Akt/mTOR Signaling

BACKGROUND: Current antidepressants in clinical use always take weeks or even months to exert full therapeutic effects, and sometimes have serious side effects. Thus, it is very necessary to develop novel antidepressants with better efficacy and fewer adverse effects. The present study focused on in...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Wu, Zhonghua, You, Zhengchen, Chen, Peng, Chen, Cheng, Chen, Fei, Shen, Jianhong, Xu, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070064/
https://ncbi.nlm.nih.gov/pubmed/29668939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyy028
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