A semantics-oriented computational approach to investigate microRNA regulation on glucocorticoid resistance in pediatric acute lymphoblastic leukemia

BACKGROUND: Acute lymphoblastic leukemia is the most prevalent neoplasia among children. Despite the tremendous achievements of state-of-the-art treatment strategies, drug resistance is still a major cause of chemotherapy failure leading to relapse in pediatric acute lymphoblastic leukemia. The unde...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Med Inform Decis Mak
Auteurs principaux: Chen, Huiqin, Zhang, Dihua, Zhang, Guoping, Li, Xiaofeng, Liang, Ying, Kasukurthi, Mohan Vamsi, Li, Shengyu, Borchert, Glen M., Huang, Jingshan
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069764/
https://ncbi.nlm.nih.gov/pubmed/30066657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12911-018-0637-3
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