Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge

Broadly cross-reactive antibodies (Abs) that recognize conserved epitopes within the influenza virus hemagglutinin (HA) stalk domain are of particular interest for their potential use as therapeutic and prophylactic agents against multiple influenza virus subtypes, including zoonotic virus strains....

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Nachbagauer, Raffael, Shore, David, Yang, Hua, Johnson, Scott K., Gabbard, Jon D., Tompkins, S. Mark, Wrammert, Jens, Wilson, Patrick C., Stevens, James, Ahmed, Rafi, Krammer, Florian, Ellebedy, Ali H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069173/
https://ncbi.nlm.nih.gov/pubmed/29899095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00949-18
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