Elicitation of Protective Antibodies against a Broad Panel of H1N1 Viruses in Ferrets Preimmune to Historical H1N1 Influenza Viruses

Most preclinical animal studies test influenza vaccines in immunologically naive animal models, even though the results of vaccination may not accurately reflect the effectiveness of vaccine candidates in humans that have preexisting immunity to influenza. In this study, novel, broadly reactive infl...

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Veröffentlicht in:J Virol
Hauptverfasser: Carter, Donald M., Darby, Christopher A., Johnson, Scott K., Carlock, Michael A., Kirchenbaum, Greg A., Allen, James D., Vogel, Thorsten U., Delagrave, Simon, DiNapoli, Joshua, Kleanthous, Harold, Ross, Ted M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709581/
https://ncbi.nlm.nih.gov/pubmed/28978709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01283-17
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