Elicitation of Protective Antibodies against a Broad Panel of H1N1 Viruses in Ferrets Preimmune to Historical H1N1 Influenza Viruses

Most preclinical animal studies test influenza vaccines in immunologically naive animal models, even though the results of vaccination may not accurately reflect the effectiveness of vaccine candidates in humans that have preexisting immunity to influenza. In this study, novel, broadly reactive infl...

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Bibliographic Details
Published in:J Virol
Main Authors: Carter, Donald M., Darby, Christopher A., Johnson, Scott K., Carlock, Michael A., Kirchenbaum, Greg A., Allen, James D., Vogel, Thorsten U., Delagrave, Simon, DiNapoli, Joshua, Kleanthous, Harold, Ross, Ted M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709581/
https://ncbi.nlm.nih.gov/pubmed/28978709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01283-17
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