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Key Residues for the Formation of Aβ42 Amyloid Fibrils

[Image: see text] Formation of amyloid fibrils by Aβ42 protein is a pathological hallmark of Alzheimer’s disease. Aβ42 fibrillization is a nucleation-dependent polymerization process, in which nucleation is the rate-limiting step. Structural knowledge of the fibril nucleus is important to understand...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Hsu, Frederick, Park, Giovanna, Guo, Zhefeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068601/
https://ncbi.nlm.nih.gov/pubmed/30087945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00887
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