Topical ferumoxytol nanoparticles disrupt biofilms and prevent tooth decay in vivo via intrinsic catalytic activity

Ferumoxytol is a nanoparticle formulation approved by the U.S. Food and Drug Administration for systemic use to treat iron deficiency. Here, we show that, in addition, ferumoxytol disrupts intractable oral biofilms and prevents tooth decay (dental caries) via intrinsic peroxidase-like activity. Feru...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Yuan, Naha, Pratap C., Hwang, Geelsu, Kim, Dongyeop, Huang, Yue, Simon-Soro, Aurea, Jung, Hoi-In, Ren, Zhi, Li, Yong, Gubara, Sarah, Alawi, Faizan, Zero, Domenick, Hara, Anderson T., Cormode, David P., Koo, Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068184/
https://ncbi.nlm.nih.gov/pubmed/30065293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05342-x
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