Topical ferumoxytol nanoparticles disrupt biofilms and prevent tooth decay in vivo via intrinsic catalytic activity

Ferumoxytol is a nanoparticle formulation approved by the U.S. Food and Drug Administration for systemic use to treat iron deficiency. Here, we show that, in addition, ferumoxytol disrupts intractable oral biofilms and prevents tooth decay (dental caries) via intrinsic peroxidase-like activity. Feru...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Liu, Yuan, Naha, Pratap C., Hwang, Geelsu, Kim, Dongyeop, Huang, Yue, Simon-Soro, Aurea, Jung, Hoi-In, Ren, Zhi, Li, Yong, Gubara, Sarah, Alawi, Faizan, Zero, Domenick, Hara, Anderson T., Cormode, David P., Koo, Hyun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068184/
https://ncbi.nlm.nih.gov/pubmed/30065293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05342-x
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