Biofilm three-dimensional architecture influences in situ pH distribution pattern on the human enamel surface

Por Xiao, Jin, Hara, Anderson T, Kim, Dongyeop, Zero, Domenick T, Koo, Hyun, Hwang, Geelsu
Publicado no Int J Oral Sci (2017)

Streptococcus mutans-derived extracellular matrix in cariogenic oral biofilms

Por Klein, Marlise I., Hwang, Geelsu, Santos, Paulo H. S., Campanella, Osvaldo H., Koo, Hyun
Publicado no Front Cell Infect Microbiol (2015)

Candida albicans mannans mediate Streptococcus mutans exoenzyme GtfB binding to modulate cross-kingdom biofilm development in vivo

Por Hwang, Geelsu, Liu, Yuan, Kim, Dongyeop, Li, Yong, Krysan, Damian J., Koo, Hyun
Publicado no PLoS Pathog (2017)

α-Mangostin Disrupts the Development of Streptococcus mutans Biofilms and Facilitates Its Mechanical Removal

Por Nguyen, Phuong Thi Mai, Falsetta, Megan L., Hwang, Geelsu, Gonzalez-Begne, Mireya, Koo, Hyun
Publicado em 2014

Cranberry Flavonoids Modulate Cariogenic Properties of Mixed-Species Biofilm through Exopolysaccharides-Matrix Disruption

Por Kim, Dongyeop, Hwang, Geelsu, Liu, Yuan, Wang, Yifei, Singh, Ajay P., Vorsa, Nicholi, Koo, Hyun
Publicado no PLoS One (2015)

Characterization and optimization of pH-responsive polymer nanoparticles for drug delivery to oral biofilms

Por Zhou, Jiayi, Horev, Benjamin, Hwang, Geelsu, Klein, Marlise I., Koo, Hyun, Benoit, Danielle S.W.
Publicado no J Mater Chem B Mater Biol Med (2015)

pH-activated Nanoparticles for Controlled Topical Delivery of Farnesol to Disrupt Oral Biofilm Virulence

Por Horev, Benjamin, Klein, Marlise I., Hwang, Geelsu, Li, Yong, Kim, Dongyeop, Koo, Hyun, Benoit, Danielle S.W.
Publicado no ACS Nano (2015)

Nanocatalysts promote Streptococcus mutans biofilm matrix degradation and enhance bacterial killing to suppress dental caries in vivo

Por Gao, Lizeng, Liu, Yuan, Kim, Dongyeop, Li, Yong, Hwang, Geelsu, Naha, Pratap C., Cormode, David P., Koo, Hyun
Publicado no Biomaterials (2016)

l-Arginine Modifies the Exopolysaccharide Matrix and Thwarts Streptococcus mutans Outgrowth within Mixed-Species Oral Biofilms

Por He, Jinzhi, Hwang, Geelsu, Liu, Yuan, Gao, Lizeng, Kilpatrick-Liverman, LaTonya, Santarpia, Peter, Zhou, Xuedong, Koo, Hyun
Publicado no J Bacteriol (2016)

Simultaneous spatiotemporal mapping of in situ pH and bacterial activity within an intact 3D microcolony structure

Por Hwang, Geelsu, Liu, Yuan, Kim, Dongyeop, Sun, Victor, Aviles-Reyes, Alejandro, Kajfasz, Jessica K., Lemos, Jose A., Koo, Hyun
Publicado no Sci Rep (2016)

Bacterial-derived exopolysaccharides enhance antifungal drug tolerance in a cross-kingdom oral biofilm

Por Kim, Dongyeop, Liu, Yuan, Benhamou, Raphael I., Sanchez, Hiram, Simón-Soro, Áurea, Li, Yong, Hwang, Geelsu, Fridman, Micha, Andes, David R., Koo, Hyun
Publicado no ISME J (2018)

Topical ferumoxytol nanoparticles disrupt biofilms and prevent tooth decay in vivo via intrinsic catalytic activity

Por Liu, Yuan, Naha, Pratap C., Hwang, Geelsu, Kim, Dongyeop, Huang, Yue, Simon-Soro, Aurea, Jung, Hoi-In, Ren, Zhi, Li, Yong, Gubara, Sarah, Alawi, Faizan, Zero, Domenick, Hara, Anderson T., Cormode, David P., Koo, Hyun
Publicado no Nat Commun (2018)