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IDO1 in cancer: a Gemini of immune checkpoints
Indoleamine 2, 3-dioxygenase 1 (IDO1) is a rate-limiting metabolic enzyme that converts the essential amino acid tryptophan (Trp) into downstream catabolites known as kynurenines. Coincidently, numerous studies have demonstrated that IDO1 is highly expressed in multiple types of human cancer. Precli...
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| Publicado no: | Cell Mol Immunol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6068130/ https://ncbi.nlm.nih.gov/pubmed/29375124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2017.143 |
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