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IMMU-35. TARGETING IDO1 IN HUMAN PEDIATRIC BRAIN CANCER
Indoleamine 2,3 dioxygenase 1 (IDO1) is a rate-limiting enzyme that converts tryptophan (Trp) into kynurenine (Kyn) and has been confirmed to suppress the immune response in adults diagnosed with malignant glioma. To address the role of IDO1 in pediatric high grade glioma (HGG), we investigated its...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5693165/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.493 |
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