Investigations on the mode of action of gephyronic acid, an inhibitor of eukaryotic protein translation from myxobacteria

The identification of inhibitors of eukaryotic protein biosynthesis, which are targeting single translation factors, is highly demanded. Here we report on a small molecule inhibitor, gephyronic acid, isolated from the myxobacterium Archangium gephyra that inhibits growth of transformed mammalian cel...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Muthukumar, Yazh, Münkemer, Johanna, Mathieu, Daniel, Richter, Christian, Schwalbe, Harald, Steinmetz, Heinrich, Kessler, Wolfgang, Reichelt, Joachim, Beutling, Ulrike, Frank, Ronald, Büssow, Konrad, van den Heuvel, Joop, Brönstrup, Mark, Taylor, Richard E., Laschat, Sabine, Sasse, Florenz
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067752/
https://ncbi.nlm.nih.gov/pubmed/30063768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201605
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars