Screening of small molecules affecting mammalian P-body assembly uncovers links with diverse intracellular processes and organelle physiology

Processing bodies (P-bodies) are cytoplasmatic mRNP granules containing non-translating mRNAs and proteins from the mRNA decay and silencing machineries. The mechanism of P-body assembly has been typically addressed by depleting P-body components. Here we apply a complementary approach and establish...

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Detalhes bibliográficos
Main Authors: Martínez, Javier P, Pérez-Vilaró, Gemma, Muthukumar, Yazh, Scheller, Nicoletta, Hirsch, Tatjana, Diestel, Randi, Steinmetz, Heinrich, Jansen, Rolf, Frank, Ronald, Sasse, Florenz, Meyerhans, Andreas, Díez, Juana
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907476/
https://ncbi.nlm.nih.gov/pubmed/24418890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.26851
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