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Aerosolizing Lipid Dispersions Enables Antibiotic Transport Across Mimics of the Lung Airway Surface Even in the Presence of Pre-existing Lipid Monolayers

Background: Secondary lung infections are the primary cause of morbidity associated with cystic fibrosis lung disease. Aerosolized antibiotic inhalation is potentially advantageous but has limited effectiveness due to altered airway aerodynamics and deposition patterns that limit drug access to infe...

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Библиографические подробности
Опубликовано в: :J Aerosol Med Pulm Drug Deliv
Главные авторы: Iasella, Steven V., Stetten, Amy Z., Corcoran, Timothy E., Garoff, Stephen, Przybycien, Todd M., Tilton, Robert D.
Формат: Artigo
Язык:Inglês
Опубликовано: Mary Ann Liebert, Inc. 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067685/
https://ncbi.nlm.nih.gov/pubmed/29053080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jamp.2017.1412
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