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Aerosolizing Lipid Dispersions Enables Antibiotic Transport Across Mimics of the Lung Airway Surface Even in the Presence of Pre-existing Lipid Monolayers

Background: Secondary lung infections are the primary cause of morbidity associated with cystic fibrosis lung disease. Aerosolized antibiotic inhalation is potentially advantageous but has limited effectiveness due to altered airway aerodynamics and deposition patterns that limit drug access to infe...

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Detalhes bibliográficos
Publicado no:J Aerosol Med Pulm Drug Deliv
Main Authors: Iasella, Steven V., Stetten, Amy Z., Corcoran, Timothy E., Garoff, Stephen, Przybycien, Todd M., Tilton, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067685/
https://ncbi.nlm.nih.gov/pubmed/29053080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jamp.2017.1412
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