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Surfactant Driven Post-Deposition Spreading of Aerosols on Complex Aqueous Subphases. 2: Low Deposition Flux Representative of Aerosol Delivery to Small Airways

Background: Cystic fibrosis (CF) is associated with the accumulation of dehydrated mucus in the pulmonary airways. This alters ventilation and aerosol deposition patterns in ways that limit drug delivery to peripheral lung regions. We investigated the use of surfactant-based, self-dispersing aerosol...

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Detalhes bibliográficos
Publicado no:J Aerosol Med Pulm Drug Deliv
Main Authors: Sharma, Ramankur, Khanal, Amsul, Corcoran, Timothy E., Garoff, Stephen, Przybycien, Todd M., Tilton, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4601626/
https://ncbi.nlm.nih.gov/pubmed/25757067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jamp.2014.1167
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