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Variability in Expression of CYP3A5 in Human Fetal Liver

Members of the cytochrome P450 3A (CYP3A) subfamily of drug metabolizing enzymes exhibit developmental changes in expression in human liver characterized by a transition between CYP3A7 and CYP3A4 over the first few years of life. In contrast, the developmental expression of CYP3A5 is less well under...

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Bibliografiska uppgifter
I publikationen:Drug Metab Dispos
Huvudupphovsmän: Vyhlidal, Carrie A., Pearce, Robin E., Gaedigk, Roger, Calamia, Justina C., Shuster, Diana L., Thummel, Kenneth E., Leeder, J. Steven
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067386/
https://ncbi.nlm.nih.gov/pubmed/25979262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.064998
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