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Adaptive Local Realignment of Protein Sequences

While mutation rates can vary markedly over the residues of a protein, multiple sequence alignment tools typically use the same values for their scoring-function parameters across a protein's entire length. We present a new approach, called adaptive local realignment, that in contrast automatic...

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Bibliographic Details
Published in:J Comput Biol
Main Authors: DeBlasio, Dan, Kececioglu, John
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067105/
https://ncbi.nlm.nih.gov/pubmed/29889553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2018.0045
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