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Accuracy Estimation and Parameter Advising for Protein Multiple Sequence Alignment

We develop a novel and general approach to estimating the accuracy of multiple sequence alignments without knowledge of a reference alignment, and use our approach to address a new task that we call parameter advising: the problem of choosing values for alignment scoring function parameters from a g...

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Bibliographic Details
Main Authors: Kececioglu, John, DeBlasio, Dan
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619150/
https://ncbi.nlm.nih.gov/pubmed/23489379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2013.0007
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