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Aspirin Induces Lysosomal Biogenesis and Attenuates Amyloid Plaque Pathology in a Mouse Model of Alzheimer's Disease via PPARα

Lysosomes play a central role in cellular homeostasis by regulating the cellular degradative machinery. Because aberrant lysosomal function has been associated with multiple lysosomal storage and neurodegenerative disorders, enhancement of lysosomal clearance has emerged as an attractive therapeutic...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Chandra, Sujyoti, Jana, Malabendu, Pahan, Kalipada
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067079/
https://ncbi.nlm.nih.gov/pubmed/29967008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0054-18.2018
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