載入...
A Novel DPYD Variant Associated With Severe Toxicity of Fluoropyrimidines: Role of Pre-emptive DPYD Genotype Screening
Background: The fluoropyrimidine anticancer drug, especially 5- fluorouracil (5-FU) and its prodrug capecitabine are still being the backbone of chemotherapeutic regimens for colorectal cancer. Dihydropyrimidine dehydrogenase (DPD) is the crucial enzyme in the catabolism of 5-FU. Over the past 30 ye...
Na minha lista:
| 發表在: | Front Oncol |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Frontiers Media S.A.
2018
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6066555/ https://ncbi.nlm.nih.gov/pubmed/30087856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00279 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|