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Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development
Epigenetic regulation is critical in normal cardiac development. We have demonstrated that the deletion of Jarid2 (Jumonji (Jmj) A/T-rich interaction domain 2) in mice results in cardiac malformations recapitulating human congenital cardiac disease and dysregulation of gene expression. However, the...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6066322/ https://ncbi.nlm.nih.gov/pubmed/29891551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002482 |
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